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1

Chronic myeloid leukemia 2011: Successes, challenges, and strategies—Proceedings of the 5th annual BCR-ABL1 positive and BCR-ABL1 negative myeloproliferative neoplasms workshop

Tariq I. Mughal, Jerald P. Radich, Richard A. Van Etten, Alfonso Quintás-Cardama, Tomasz Skorski, Farhad Ravandi, Daniel J. DeAngelo, Carlo Gambacorti-Passerini, Giovanni Martinelli, Ayalew Tefferi

Journal:

American Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 148 KB

english, 2011

2

10.1038/20061

Gambacorti-Passerini, Carlo

Journal:

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

3

Part I: Milestones in personalised medicine—imatinib

Carlo Gambacorti-Passerini

Journal:

The Lancet Oncology

Year:

2008

Language:

english

File:

PDF, 76 KB

english, 2008

4

Structural Insights into the ATP Binding Pocket of the Anaplastic Lymphoma Kinase by Site-Directed Mutagenesis, Inhibitor Binding Analysis, and Homology Modeling

Gunby, Rosalind H., Ahmed, Shaheen, Sottocornola, Roberta, Gasser, Marc, Redaelli, Sara, Mologni, Luca, Tartari, Carmen J, Belloni, Valentina, Gambacorti-Passerini, Carlo, Scapozza, Leonardo

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 897 KB

english, 2006

5

Pregnancy outcomes in patients treated with bosutinib

Cortes, Jorge E, Gambacorti-Passerini, Carlo, Deininger, Michael, Abruzzese, Elisabetta, DeAnnuntis, Liza, BrÃ¼mmendorf, Tim H

Journal:

International Journal of Hematologic Oncology

Year:

2020

File:

PDF, 290 KB

2020

6

Simultaneous development of Philadelphia chromosome-positive and -negative leukemias in the same patient

Sarit Assouline, Valerie Benemacher, Carlo Gambacorti-Passerini

Journal:

American Journal of Hematology

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

7

ChemInform Abstract: Inhibitors of the RET Tyrosine Kinase Based on a 2-(Alkylsulfanyl)-4-(3-thienyl) Nicotinonitrile Scaffold.

Wiebke Brandt, Luca Mologni, Lutz Preu, Thomas Lemcke, Carlo Gambacorti-Passerini, Conrad Kunick

Journal:

Year:

2010

Language:

english

File:

PDF, 38 KB

english, 2010

8

Design, Synthesis, and Biological Activity of Urea Derivatives as Anaplastic Lymphoma Kinase Inhibitors

Gustav Boije af Gennäs, Dr. Luca Mologni, Dr. Shaheen Ahmed, Dr. Mohanathas Rajaratnam, Prof. Oriano Marin, Niko Lindholm, Michela Viltadi, Prof. Carlo Gambacorti-Passerini, Prof. Leonardo Scapozza, P

Journal:

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

9

The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in philadelphia chromosome-negative cells

Michael W. N. Deininger, Jorge Cortes, Ron Paquette, Byung Park, Andreas Hochhaus, Michele Baccarani, Richard Stone, Thomas Fischer, Hagop Kantarjian, Dietger Niederwieser, Carlo Gambacorti-Passerini,

Journal:

Year:

2007

Language:

english

File:

PDF, 380 KB

english, 2007

10

Molecular cytogenetics of the acute promyelocytic leukemia-derived cell line NB4 and of four all-trans retinoic acid–resistant subclones

Marie-Joëlle Mozziconacci, Angelika Rosenauer, Audrey Restouin, Mirco Fanelli, Wenlin Shao, Francisca Fernandez, Yves Toiron, Jeanine Viscardi, Carlo Gambacorti-Passerini, Wilson H. Miller Jr., Marina

Journal:

Genes, Chromosomes and Cancer

Year:

2002

Language:

english

File:

PDF, 2.96 MB

english, 2002

11

Valproic acid enhances bosutinib cytotoxicity in colon cancer cells

Luca Mologni, Loredana Cleris, Vera Magistroni, Rocco Piazza, Frank Boschelli, Franca Formelli, Carlo Gambacorti-Passerini

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 401 KB

english, 2009

12

In vivo activation of lymphocytes in melanoma patients receiving escalating doses of recombinant interleukin 2

Carlo Gambacorti-Passerini, Marina Radrizzani, Raffaele Marolda, Filiberto Belli, Gianalfredo Sciorelli, Andrew R. Galazka, John D. Schindler, Natale Cascinelli, Giorgio Parmiani

Journal:

International Journal of Cancer

Year:

1988

Language:

english

File:

PDF, 705 KB

english, 1988

13

Differential lysis of melanoma clones by autologous recombinant interleukin 2-activated lymphocytes. Relationship with spontaneous resistance to doxorubicin (Dx)

Carlo Gambacorti-Passerini, Licia Rivoltini, Rosanna Supino, Mariangela Mariani, Giorgio Parmiani

Journal:

International Journal of Cancer

Year:

1988

Language:

english

File:

PDF, 513 KB

english, 1988

14

Generation and partial characterization of melanoma sublines resistant to lymphokine activated killer (LAK) cells. Relevance to doxorubicin resistance

Licia Rivoltini, Carlo Gambacorti-Passerini, Rosanna Supino, Giorgio Parmiani

Journal:

International Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 1.14 MB

english, 1989

15

Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl)nicotinonitrile scaffold

Wiebke Brandt, Luca Mologni, Lutz Preu, Thomas Lemcke, Carlo Gambacorti-Passerini, Conrad Kunick

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 665 KB

english, 2010

16

Imatinib does not substantially modify the glycemic profile in patients with chronic myeloid leukaemia

Stefania Mariani, Lucia Tornaghi, Marianna Sassone, Sabrina Basciani, Raffaella Buzzetti, Carlo Gambacorti-Passerini, Giovanni Spera, Lucio Gnessi

Journal:

Leukemia Research

Year:

2010

Language:

english

File:

PDF, 219 KB

english, 2010

17

BCR-ABL oncoprotein is expressed by platelets from CML patients and associated with a special pattern of CrkL phosphorylation

George J. A. Ten Bosch, Jan H. Kessler, Johanna Blom, Antonia M. Joosten, Carlo Gambacorti-Passerini, Cornelis J. M. Melief, Onno C. Leeksma

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 263 KB

english, 1998

18

Sensitivity to the abl inhibitor STI571 in fresh leukaemic cells obtained from chronic myelogenous leukaemia patients in different stages of disease

Carlo Gambacorti-Passerini, Rossella Barni, Edoardo Marchesi, Magda Verga, Francesca Rossi, Fabio Rossi, Pietro Pioltelli, Enrico Pogliani, Gian Marco Corneo

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

19

Autologous cellular immune response to primary and metastatic human melanomas and its regulation by DR antigens expressed on tumor cells

Giorgio Parmiani, Giuseppe Fossati, Donatella Taramelli, Andrea Anichini, Andrea Balsari, Carlo Gambacorti-Passerini, Gianalfredo Sciorelli, Natale Cascinelli

Journal:

Cancer and Metastasis Reviews

Year:

1985

Language:

english

File:

PDF, 1.61 MB

english, 1985

20

Susceptibility of human and murine drug-resistant tumor cells to the lytic activity of rIL2 - activated lymphocytes (LAK)

Carlo Gambacorti-Passerini, Licia Rivoltini, Marina Radrizzani, Rosanna Supino, Mariangela Mariani, Giorgio Parmiani

Journal:

Cancer and Metastasis Reviews

Year:

1988

Language:

english

File:

PDF, 708 KB

english, 1988

21

Systemic administration of autologous, alloactivated helper-enriched lymphocytes to patients with metastatic melanoma of the lung

Andrea Balsari, Raffaele Marolda, Carlo Gambacorti-Passerini, Gianalfredo Sciorelli, Gabriella Tona, Elisabetta Cosulich, Donatella Taramelli, Giuseppe Fossati, Giorgio Parmiani, Natale Cascinelli

Journal:

Cancer Immunology, Immunotherapy

Year:

1986

Language:

english

File:

PDF, 965 KB

english, 1986

22

Lysis by interleukin 2-stimulated tumor-infiltrating lymphocytes of autologous and allogeneic tumor target cells

Marina Radrizzani, Carlo Gambacorti-Passerini, Giorgio Parmiani, Giuseppe Fossati

Journal:

Cancer Immunology, Immunotherapy

Year:

1989

Language:

english

File:

PDF, 777 KB

english, 1989

23

Adoptive immunotherapy of advanced melanoma patients with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes selected in vitro with low doses of IL-2

Flavio Arienti, Filiberto Belli, Licia Rivoltini, Carlo Gambacorti-Passerini, Luigi Furlan, Luigi Mascheroni, Augusto Prada, Maurilia Rizzi, Edoardo Marchesi, Maurizio Vaglini, Giorgio Parmiani, Natal

Journal:

Cancer Immunology, Immunotherapy

Year:

1993

Language:

english

File:

PDF, 890 KB

english, 1993

24

PNAs as novel cancer therapeutics

Luca Mologni, Carlo Gambacorti-Passerini

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 1.26 MB

english, 2003

25

Immunogenicity of fusion proteins

Carlo Gambacorti-Passerini

Journal:

International Journal of Clinical & Laboratory Research

Year:

1993

Language:

english

File:

PDF, 590 KB

english, 1993

26

Adoptive immunotherapy of cancer with immune and activated lymphocytes: Experimental and clinical studies

Giorgio Parmiani, Maria Luisa Sensi, Andrea Balsari, Mario P. Colombo, Carlo Gambacorti-Passerini, Laura Grazioli, Monica Rodolfo, Natale Cascinelli, Giuseppe Fossati

Journal:

International Journal of Clinical & Laboratory Research

Year:

1986

Language:

english

File:

PDF, 1.32 MB

english, 1986

27

PNAs as novel cancer therapeutics

Luca Mologni, Carlo Gambacorti-Passerini

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

28

Peripheral blood progenitor cell collection in chronic myeloid leukemia patients with complete cytogenetic response after treatment with imatinib mesylate

Paolo Perseghin, Carlo Gambacorti-Passerini, Lucia Tornaghi, Maria Dassi, Pietro Pioltelli, Matteo Parma, Federica Colnaghi, Giovanni Giudici, Elena Elli, Monica Fumagalli, Luisa Ponchio, Andrea Biond

Journal:

Transfusion (Wiley)

Year:

2005

Language:

english

File:

PDF, 89 KB

english, 2005

29

BCR-ABL suppresses C/EBPα expression through inhibitory action of hnRNP E2

Perrotti, Danilo, Cesi, Vincenzo, Trotta, Rossana, Guerzoni, Clara, Santilli, Giorgia, Campbell, Kenneth, Iervolino, Angela, Condorelli, Fabrizio, Gambacorti-Passerini, Carlo, Caligiuri, Michael A.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1013 KB

english, 2002

30

Corrigendum: In reply to 'Cardiotoxicity of the cancer therapeutic agent imatinib mesylate'

Gambacorti-Passerini, Carlo, Tornaghi, Lucia, Franceschino, Anna, Piazza, Rocco, Corneo, Gianmarco, Pogliani, Enrico

Journal:

Nature Medicine

Year:

2007

File:

PDF, 43 KB

2007

31

Bcr-Abl stabilizes β-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

Coluccia, Addolorata Maria Luce, Vacca, Angelo, Duñach, Mireia, Mologni, Luca, Redaelli, Sara, Bustos, Victor H, Benati, Daniela, Pinna, Lorenzo A, Gambacorti-Passerini, Carlo

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 541 KB

english, 2007

32

Choosing the right TKI for chronic myeloid leukemia: When the truth lies in “long-term” safety and efficacy

Carlo Gambacorti-Passerini, Rocco Piazza

Journal:

American Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

33

Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells

Gabriella Marfe, Carla Di Stefano, Alessandra Gambacurta, Tiziana Ottone, Valentina Martini, Elisabetta Abruzzese, Luca Mologni, Paola Sinibaldi-Salimei, Paolo de Fabritis, Carlo Gambacorti-Passerini,

Journal:

Experimental Hematology

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

34

Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells

Holger Ruchatz, Addolorata Maria Luce Coluccia, Paola Stano, Edoardo Marchesi, Carlo Gambacorti-Passerini

Journal:

Experimental Hematology

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

35

Selective purging by human interleukin-2 activated lymphocytes of bone marrows contaminated with a lymphoma line or autologous leukaemic cells

Carlo Gambacorti-Passerini, Licia Rivoltini, Marco Fizzotti, Monica Rodolfo, Maria Luisa Sensi, Chiara Castelli, Attilio Orazi, Nicoletta Polli, Marco Bregni, Salvatore Siena, Lorenza Borin, Enrico Po

Journal:

British Journal of Haematology

Year:

1991

Language:

english

File:

PDF, 848 KB

english, 1991

36

Effects of 1,25-Dihydroxy Vitamin D3 on All-Trans Retinoic Acid Sensitive and Resistant Acute Promyelocytic Leukemia Cells

Maurizio Gianni’, Mineko Terao, Carlo Gambacorti-Passerini, Alessandro Rambaldi, Enrico Garattini

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 125 KB

english, 1996

37

In Vitro Transcriptional and Translational Block of the bcl-2 Gene Operated by Peptide Nucleic Acid

Luca Mologni, Peter E. Nielsen, Carlo Gambacorti-Passerini

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

38

Inhibition of the ABL Kinase Activity Blocks the Proliferation of BCR/ABL+Leukemic Cells and Induces Apoptosis

Carlo Gambacorti-Passerini, Philipp le Coutre, Luca Mologni, Mirco Fanelli, Carla Bertazzoli, Edoardo Marchesi, Massimo Di Nicola, Andrea Biondi, Gian Marco Corneo, Daniela Belotti, Enrico Pogliani, N

Journal:

Blood Cells, Molecules, and Diseases

Year:

1997

Language:

english

File:

PDF, 239 KB

english, 1997

39

Determination of α-1 Acid Glycoprotein in Patients with Ph+ Chronic Myeloid Leukemia during the First 13 Weeks of Therapy with STI571

Philipp le Coutre, Karl-Anton Kreuzer, Il-Kang Na, Joachim Lupberger, Matthias Holdhoff, Christine Appelt, Michaela Schwarz, Christian Müller, Carlo Gambacorti-Passerini, Uwe Platzbecker, Ragnhild Bon

Journal:

Blood Cells, Molecules, and Diseases

Year:

2002

Language:

english

File:

PDF, 95 KB

english, 2002

40

Differences between in Vivo and in Vitro Sensitivity to Imatinib of Bcr/Abl+ Cells Obtained from Leukemic Patients

Carlo B. Gambacorti-Passerini, Francesca Rossi, Magda Verga, Holger Ruchatz, Rosalind Gunby, Roberta Frapolli, Massimo Zucchetti, Leonardo Scapozza, Silvia Bungaro, Lucia Tornaghi, Fabio Rossi, Pietro

Journal:

Blood Cells, Molecules, and Diseases

Year:

2002

Language:

english

File:

PDF, 312 KB

english, 2002

41

The achievement of durable complete cytogenetic remission in late chronic and accelerated phase patients with CML treated with Imatinib mesylate predicts for prolonged response at 6 years

Rocco G. Piazza, Vera Magistroni, Anna Franceschino, Federica Andreoni, Lucia Tornaghi, Federica Colnaghi, Gianmarco Corneo, Enrico M. Pogliani, Carlo Gambacorti-Passerini

Journal:

Blood Cells, Molecules, and Diseases

Year:

2006

Language:

english

File:

PDF, 111 KB

english, 2006

42

Bosutinib: A review of preclinical studies in chronic myelogenous leukaemia

Frank Boschelli, Kim Arndt, Carlo Gambacorti-Passerini

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 282 KB

english, 2010

43

A rapid method for the purification of wild-type and V804M mutant ret catalytic domain: A tool to study thyroid cancer

Elisa Sala, Luca Mologni, Sara Cazzaniga, Elena Papinutto, Carlo Gambacorti-Passerini

Journal:

International Journal of Biological Macromolecules

Year:

2006

Language:

english

File:

PDF, 322 KB

english, 2006

44

Expression, purification, and inhibition of human RET tyrosine kinase

Luca Mologni, Elisa Sala, Barbara Riva, Luca Cesaro, Sara Cazzaniga, Sara Redaelli, Oriano Marin, Nicola Pasquato, Arianna Donella-Deana, Carlo Gambacorti-Passerini

Journal:

Protein Expression and Purification

Year:

2005

Language:

english

File:

PDF, 363 KB

english, 2005

45

Decrease of resistance to imatinib in leukaemia

Carlo Gambacorti-Passerini

Journal:

Year:

2002

Language:

english

File:

PDF, 47 KB

english, 2002

46

Gynaecomastia in men with chronic myeloid leukaemia after imatinib

Carlo Gambacorti-Passerini, Lucia Tornaghi, Francesco Cavagnini, Pellegrino Rossi, Francesca Pecori-Giraldi, Luigi Mariani, Nadia Cambiaghi, Enrico Pogliani, Gianmarco Corneo, Lucio Gnessi

Journal:

Year:

2003

Language:

english

File:

PDF, 482 KB

english, 2003

47

Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells

Valentina Zuco, Rosanna Supino, Sabina C Righetti, Loredana Cleris, Edoardo Marchesi, Carlo Gambacorti-Passerini, Franca Formelli

Journal:

Year:

2002

Language:

english

File:

PDF, 145 KB

english, 2002

48

Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias

Carlo B Gambacorti-Passerini, Rosalind H Gunby, Rocco Piazza, Annamaria Galietta, Roberta Rostagno, Leonardo Scapozza

Journal:

The Lancet Oncology

Year:

2003

Language:

english

File:

PDF, 2.07 MB

english, 2003

49

Phenotypic and functional analysis of lymphocytes infiltrating paediatric tumours, with a characterization of the tumour phenotype

Licia Rivoltini, Flavio Arienti, Attilio Orazi, Graziella Cefalo, Marco Gasparini, Carlo Gambacorti-Passerini, Franca Fossati-Bellani, Giorgio Parmiani

Journal:

Cancer Immunology, Immunotherapy

Year:

1992

Language:

english

File:

PDF, 1.36 MB

english, 1992

50

Three novel patient-derived BCR/ABL mutants show different sensitivity to second and third generation tyrosine kinase inhibitors

Redaelli, Sara, Mologni, Luca, Rostagno, Roberta, Piazza, Rocco, Magistroni, Vera, Ceccon, Monica, Viltadi, Michela, Flynn, Daniel, Gambacorti-Passerini, Carlo

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 199 KB

english, 2012